She made her opera debut at the Finnish National Opera in the role of Mimi in Puccini's La Bohème and has since gone on to garner praise from critics and audiences alike in Vienna, Hamburg, Berlin and Bavaria, at the Opéra Bastille in Paris, at the Covent Garden in London, and at the New York Metropolitan Opera. She regularly performs at high-profile international music festivals, including Salzburg, Savonlinna, Edinburgh and Orange. Soile Isokoski enjoys a close collaboration with numerous distinguished conductors, including Esa-Pekka Salonen, Seiji Ozawa, Sir Colin Davis, Sir Simon Rattle, James Levine and Zubin Mehta.
Soile Isokoski has a wide concert repertoire. Together with her regular accompanist Marita Viitasalo, she gives lied recitals performing across Europe, Japan and the United States. The duo have also recorded works by Schubert, Schumann and a number of Finnish and Scandinavian composers, as well as Hugo Wolf's Italian Songbook with baritone Bo Skovhus. Her other releases include several critically acclaimed, award-winning opera and oratorio recordings.
Her artistic achievements and contribution to the promotion of Finnish music internationally have won Soile Isokoski a number of honours, including the Pro Finlandia Medal of the Order of the Lion of Finland in 2002, the State Prize for Music in 2005 and the Sibelius Medal in 2007.